On May 22, 1843, a significant milestone in American expansion occurred as a group of around a thousand pioneers embarked on a journey from Missouri to Oregon, known as the Great Emigration. Utilizing the Oregon Trail, these settlers faced immense hardships to seek new opportunities in the West. This mass migration not only underscored the rugged determination of American settlers but also significantly contributed to the westward expansion of the United States, influencing the later development of these regions and the eventual shape of the nation.